AI summary · arXiv: 1606.00261v1 · q-bio.TO

Relationship between Periodontal disease and Asthma among overweight/obese adults

Roberto Rivera, Oelisoa M. Andriankaja, Cynthia M. Perez, Kaumudi Joshipura

Original paper · DOI Submitted to arXiv on 07 May. 2016 License: NONEXCLUSIVE-DISTRIB 1.0

The essentials

  • The study investigated the relationship between oral health and asthma among overweight or obese adults aged 40-65 years.
  • Data from 1,315 participants were analyzed, with asthma being self-reported and periodontitis, bleeding on probing (BOP), and plaque index determined by clinical examinations.
  • Participants with severe periodontitis had lower odds of having asthma compared to those with none/mild periodontitis.
  • The proportion of BOP sites and plaque index were not statistically significant in relation to asthma.
  • For a participant with severe periodontitis, the odds ratio of taking asthma medication was lower than that of a participant with none/mild periodontitis.
  • The proportion of BOP sites was associated with the use of asthma medication while plaque index remained non-significant.
  • The hygiene hypothesis may explain this relationship as it suggests that exposure to bacteria during childhood can reduce the risk of developing allergies and autoimmune diseases later in life.
  • Further research is needed to confirm these findings and explore potential mechanisms underlying this association between oral health and respiratory conditions such as asthma.
  • Study investigated oral health & asthma in overweight/obese adults aged 40-65
  • Data from 1,315 participants analyzed: self-reported asthma & clinical exams for periodontitis, BOP & plaque index
  • Severe periodontitis linked to lower odds of having asthma compared to none/mild
  • Proportion of BOP sites & plaque index not significant in relation to asthma
  • Odds ratio for taking asthma medication lower for severe vs. none/mild periodontitis
  • Proportion of BOP sites associated with use of asthma medication; plaque index not significant
  • Hygiene hypothesis may explain link between oral health & respiratory conditions like asthma
  • Further research needed to confirm findings & explore potential mechanisms

Key points written by AI: they may contain errors, check them against the paper.

AI-generated keywords: Oral Health Asthma Overweight Obese Hygiene Hypothesis

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  • Original abstract
This study aimed to investigate the relationship between oral health and asthma among overweight or obese adults aged 40-65 years. The data from 1,315 participants were analyzed, with asthma being self-reported and periodontitis, bleeding on probing (BOP), and plaque index determined by clinical examinations. Logistic regression was used to adjust for gender, smoking status, age, body mass index, family history of asthma, and income level. The results showed that participants with severe periodontitis had lower odds of having asthma compared to those with none/mild periodontitis (odds ratio [OR] = 0.44; 95% confidence interval [CI]: 0.27-0.70). However, the proportion of BOP sites and plaque index were not statistically significant in relation to asthma. Furthermore, for a participant with severe periodontitis, the OR of taking asthma medication was lower than that of a participant with none/mild periodontitis (OR = 0.20; 95% CI: 0.09-0.43). Interestingly, the proportion of BOP sites was associated with the use of asthma medication while plaque index remained non-significant. In conclusion, this study found an inverse association between severe periodontitis and asthma among overweight or obese adults aged 40-65 years. The hygiene hypothesis may explain this relationship as it suggests that exposure to bacteria during childhood can reduce the risk of developing allergies and autoimmune diseases later in life. Further research is needed to confirm these findings and explore potential mechanisms underlying this association between oral health and respiratory conditions such as asthma.

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