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Abstract: We introduce a quantum dynamic programming framework that allows us to directly extend to the quantum realm a large body of classical dynamic programming algorithms. The corresponding quantum dynamic programming algorithms retain the same space complexity as their classical counterpart, while achieving a computational speedup. For a combinatorial (search or optimization) problem P and an instance I of P, such a speedup can be expressed in terms of the average degree δ of the {dependency digraph} G_𝒫(I) of I, determined by a recursive formulation of P. The nodes of this graph are the subproblems of P induced by I and its arcs are directed from each subproblem to those on whose solution it relies. In particular, our framework allows us to solve the considered problems in Õ(|V(G_𝒫(I))| √δ) time. As an example, we obtain a quantum version of the Bellman-Ford algorithm for computing shortest paths from a single source vertex to all the other vertices in a weighted n-vertex digraph with m edges that runs in Õ(n√{nm}) time, which improves the best known classical upper bound when m ∈ Ω(n^{1.4}).