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Trans Fatty Acids and Cardiovascular Disease

Dariush Mozaffarian (Brigham and Women's Hospital, Harvard University), Mira Katan (Wageningen University & Research), Alberto Ascherio (Harvard University), Meir J. Stampfer (Harvard University), Walter Churchill Willett (Harvard University)

New England Journal of Medicine
License: not stated (all rights reserved)

Abstract: The intake of trans fat has been associated with coronary heart disease, sudden death from cardiac causes, and diabetes. This article reviews the evidence for physiological and cellular effects of trans fatty acids, unsaturated fatty acids with at least one double bond in the trans configuration. The authors consider the feasibility and potential implications of reducing or eliminating the consumption of trans fatty acids from partially hydrogenated vegetable oils in the United States.

Published on 12 Apr. 2006