Résultats de recherche pour « Open Addressing »

This course, called Open as Antidote – addressing the big challenges facing science, was part of the 2026 FORCE11 Scholarly Communication Institute which ran with the theme of 'FSCI2026: Critical Thinking and evolving open scholarship in the era of AI' These blog posts are a series of 'explainer' pre-reading to start participants thinking about the issues the course considered in relation to the general decline of scholarly publishing.

This course, called Open as Antidote – addressing the big challenges facing science, was part of the 2026 FORCE11 Scholarly Communication Institute which ran with the theme of 'FSCI2026: Critical Thinking and evolving open scholarship in the era of AI' These blog posts are a series of 'explainer' pre-reading to start participants thinking about the issues the course considered in relation to the general decline of scholarly publishing.

Aims We often have patients who are admitted to the ward wearing only the clothes they came in. These patients have no way of going to get more clothes due to being detained, poverty/ homelessness or covid restrictions. Many do not have friends or family who can bring them clothes. As such they might wear one set of clothes for a number of weeks which is bad for their physical and mental health. We are creating a clothes bank to provide a change of clothes for these patients, and help their recovery back into the community. Many have clothes that are inappropriate for the current weather, or do not have a set of smart enough clothes for a job interview. We feel that this simple intervention will have a big community impact. Method We have obtained support from a number of charities and companies to supply donations. The project will be led by a team of staff and patients. Result We will review the usage of this scheme in 6 months time Conclusion We hope this intervention will tackle the issue of clothing on mental health wards. In the future we wish to expand this to outpatient mental health service users. We would then like to expand this project countrywide as are unaware of any other areas providing something similar.

Synthetic biology emerged as an engineering discipline to design and construct artificial biological systems. Synthetic biological designs aim to achieve specific biological behavior, which can be exploited for biotechnological, medical and industrial purposes. In addition, mimicking natural systems using well-characterized biological parts also provides powerful experimental systems to study evolution at the molecular and systems level. A strength of synthetic biology is to go beyond nature’s toolkit, to test alternative versions and to study a particular biological system and its phenotype in isolation and in a quantitative manner. Here, we review recent work that implemented synthetic systems, ranging from simple regulatory circuits, rewired cellular networks to artificial genomes and viruses, to study fundamental evolutionary concepts. In particular, engineering, perturbing or subjecting these synthetic systems to experimental laboratory evolution provides a mechanistic understanding on important evolutionary questions, such as: Why did particular regulatory networks topologies evolve and not others? What happens if we rewire regulatory networks? Could an expanded genetic code provide an evolutionary advantage? How important is the structure of genome and number of chromosomes? Although the field of evolutionary synthetic biology is still in its teens, further advances in synthetic biology provide exciting technologies and novel systems that promise to yield fundamental insights into evolutionary principles in the near future.