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Decision letter: Loss of Kat2a enhances transcriptional noise and depletes acute myeloid leukemia stem-like cells
DOI: 10.7554/elife.51754.sa1 (Medicine)
Licence : CC BY
Résumé : Histone acetyl-transferase Kat2a preserves leukemia stem cells through frequent transcriptional firing of metabolic and regulatory gene promoters and maintenance of a largely invariant self-renewal program.
Publié le 05 Oct. 2019