Exécution de notre outil de synthèse sur un nouvel article
Vérifiez l’article ci-dessous, puis lancez sa synthèse.
Contribution of ictal-interictal SPECT and SISCOM to preoperative localization of the epileptogenic zone in frontal lobe epilepsy
Lauro Wichert‐Ana (Universidade de São Paulo), Ricardo Fernandes do Amaral (Universidade de São Paulo), J. C. T. Fernandes (Universidade de São Paulo), Felipe Arriva Pitella (Universidade de São Paulo), Felipe Alves Mourato (Universidade Federal de Pernambuco, Hospital das Clínicas da Universidade Federal de Pernambuco), Mery Kato (Universidade de São Paulo), Tonicarlo Rodrigues Velasco (Universidade de São Paulo), Frederico Nakane Nakano (Universidade de São Paulo), Marina Teixeira Ramalho Pereira Dalio (Universidade de São Paulo), Veriano Alexandre (Universidade de São Paulo), Úrsula Thomé (Universidade de São Paulo), Ana Paula Andrade Hamad (Universidade de São Paulo), Antonio Carlos (Universidade de São Paulo), Américo Ceiki Sakamoto (Universidade de São Paulo)
Résumé : Objective: To describe the contributions of conventional single-photon emission computed tomography (SPECT) and subtraction ictal-interictal SPECT coregistered to magnetic resonance imaging (SISCOM) for the preoperative identification of the epileptogenic zone (EZ) in patients with frontal lobe epilepsy (FLE). Materials and methods: In this retrospective study, we reviewed medical records of all patients with refractory FLE who underwent frontal lobectomy at our institution between 2015 and 2020, all of whom had undergone at least one ictal SPECT, one interictal SPECT, one high-resolution magnetic resonance imaging examination, SISCOM, and at least one year of follow-up. Fourteen patients met the inclusion criteria. Results: After a mean follow-up of 32 months (range, 14-60 months), surgical outcomes were classified as good in five patients (35.7%) and poor in nine (64.3%). For localizing the EZ, SISCOM achieved the highest sensitivity (80%), negative predictive value (85%), and overall diagnostic accuracy (71%), whereas ictal SPECT had the highest specificity (70%) and interictal SPECT had the lowest performance overall. Conclusion: In patients with FLE, ictal and interictal SPECT alone do not seem to predict the surgical outcome. However, SISCOM seems to perform better for that purpose.