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Two Monoclonal Antibodies against Epstein-Barr Virus Proteins

Ching-Hwa Ann Tsai (The Ohio State University), Ronald Glaser (The Ohio State University)

Humana Press eBooks
Licence : non indiquée (tous droits réservés)

Résumé : The ability of viruses to produce malignant disease in humans has been intensively studied in recent years. One of these candidate viruses is the Epstein-Barr virus (EBV). The EBV is the causative agent of infectious mononucleosis (IM), and is associated with African Burkitt’s lymphoma and nasopharyngeal carcinoma (NPC). The EBV can transform human and certain non-human primate B-lympho-cytes in vitro . Understanding the biological properties of EBV may be important to the understanding of tumor induction. The use of EBV-specific monoclonal antibodies (mAb)s to study the nature of EBV proteins is one way to examine the mechanism underlying the biological properties of the virus (1). These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Publié le 01 Jan. 1987