A Comparative Study in Surgical AI: Datasets, Foundation Models, and Barriers to Med-AGI

Authors: Kirill Skobelev, Eric Fithian, Yegor Baranovski, Jack Cook, Sandeep Angara, Shauna Otto, Zhuang-Fang Yi, John Zhu, Daniel A. Donoho, X. Y. Han, Neeraj Mainkar, Margaux Masson-Forsythe

License: CC BY-NC-SA 4.0

Abstract: Recent Artificial Intelligence (AI) models have matched or exceeded human experts in several benchmarks of biomedical task performance, but have lagged behind on surgical image-analysis benchmarks. Since surgery requires integrating disparate tasks -- including multimodal data integration, human interaction, and physical effects -- generally-capable AI models could be particularly attractive as a collaborative tool if performance could be improved. On the one hand, the canonical approach of scaling architecture size and training data is attractive, especially since there are millions of hours of surgical video data generated per year. On the other hand, preparing surgical data for AI training requires significantly higher levels of professional expertise, and training on that data requires expensive computational resources. These trade-offs paint an uncertain picture of whether and to-what-extent modern AI could aid surgical practice. In this paper, we explore this question through a case study of surgical tool detection using state-of-the-art AI methods available in 2026. We demonstrate that even with multi-billion parameter models and extensive training, current Vision Language Models fall short in the seemingly simple task of tool detection in neurosurgery. Additionally, we show scaling experiments indicating that increasing model size and training time only leads to diminishing improvements in relevant performance metrics. Thus, our experiments suggest that current models could still face significant obstacles in surgical use cases. Moreover, some obstacles cannot be simply ``scaled away'' with additional compute and persist across diverse model architectures, raising the question of whether data and label availability are the only limiting factors. We discuss the main contributors to these constraints and advance potential solutions.

Submitted to arXiv on 28 Mar. 2026

Explore the paper tree

Click on the tree nodes to be redirected to a given paper and access their summaries and virtual assistant

Also access our AI generated Summaries, or ask questions about this paper to our AI assistant.

Look for similar papers (in beta version)

By clicking on the button above, our algorithm will scan all papers in our database to find the closest based on the contents of the full papers and not just on metadata. Please note that it only works for papers that we have generated summaries for and you can rerun it from time to time to get a more accurate result while our database grows.