Modelling and Analysis of Magnetic Fields from Skeletal Muscle for Valuable Physiological Measurements

Authors: Siming Zuo, Kianoush Nazarpour, Dario Farina, Philip Broser, Hadi Heidari

To be submitted to Nature Protocols. 37 Pages and includes 10 figures
License: CC BY 4.0

Abstract: MagnetoMyoGraphy (MMG) is a method of studying muscle function via weak magnetic fields generated from human active organs and tissues. The correspondence between MMG and electromyography means directly derived from the Maxwell-Amp\`ere law. Here, upon briefly describing the principles of voltage distribution inside skeletal muscles due to the electrical stimulation, we provide a protocol to determine the effects of the magnetic field generated from a time-changing action potential propagating in a group of skeletal muscle cells. The position-dependent and the magnetic field behaviour on account of the different currents in muscle fibres are performed in temporal, spectral and spatial domains. The procedure covers identification of the fibre subpopulations inside the fascicles of a given nerve section, characterization of soleus skeletal muscle currents, check of axial intracellular currents, calculation of the generated magnetic field ultimately. We expect this protocol to take approximately 2-3 hours to complete for the whole finite-element analysis.

Submitted to arXiv on 05 Apr. 2021

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