# Dietary Supplements and Nutraceuticals Under Investigation for COVID-19 Prevention and Treatment

**Authors:** Ronan Lordan, Halie M. Rando, COVID-19 Review Consortium, Casey S. Greene  
**arXiv:** [2102.02250](https://arxiv.org/abs/2102.02250)  
**Date:** 2021-02-03  
**Summary page:** https://www.summarizepaper.com/en/paper/2102.02250v1/

## Key points

- COVID-19 pandemic has caused widespread disruption and loss of life
- Interest in exploring dietary supplements and nutraceuticals for prevention and treatment of COVID-19
- Products under investigation include vitamin C, vitamin D, omega 3 fatty acids, probiotics, and zinc
- Nutritional status plays a crucial role in patient outcomes
- Vitamin D deficiency may be associated with higher incidence of infection and more severe cases of COVID-19
- Research on dietary supplements and nutraceuticals is still in early stages
- Scientific organizations considering recommending certain supplements like vitamin D to those at risk but guidelines are yet to be established
- Further study is required before definitive conclusions can be drawn on the effectiveness of these products for COVID-19 prevention and treatment
- Individuals seeking information related to COVID-19 should consult reliable sources such as local health departments or official guidance from organizations like the CDC or their respective governments

## Summary

The coronavirus disease 2019 (COVID-19) pandemic has caused widespread disruption and a significant loss of life. As the search for effective treatments continues, there is growing interest in exploring the potential of dietary supplements and nutraceuticals for both prevention and treatment of COVID-19. Some of the products currently under investigation include vitamin C, vitamin D, omega 3 polyunsaturated fatty acids, probiotics, and zinc. While further research is needed to establish evidence-based recommendations, it is known that nutritional status plays a crucial role in patient outcomes. For example, studies have suggested that vitamin D deficiency may be associated with a higher incidence of infection and more severe cases of COVID-19. This has led to discussions about the potential prophylactic or therapeutic value of vitamin D supplementation, especially for individuals at high risk. It is important to note that research on these dietary supplements and nutraceuticals is still in its early stages. Therefore, it is necessary to evaluate their potential within the context of the COVID-19 crisis. Scientific organizations are increasingly considering recommending certain supplements like vitamin D to those at risk but concrete guidelines are yet to be established. This review paper aims to critically appraise the existing evidence surrounding dietary supplements and nutraceuticals for COVID-19 prevention and treatment. While these products may help alleviate deficiencies and improve patient outcomes, further study is required before definitive conclusions can be drawn. It is essential for individuals seeking information related to testing, therapies or other health issues regarding COVID-19 to consult reliable sources such as local health departments or official guidance from organizations like the CDC or their respective governments. The authors of this manuscript are scientists contributing to ongoing research efforts in understanding COVID-19. The manuscript serves as a discussion among scientists rather than being intended for general public consumption.